Corynebacterium lilium

Methionine is overproduced by auxotrophic and analogue-resistant mutants. E. coli K-12 mutant resistant to methionine analogues (norleucine, ethionine, and methyl methionine) produced 2mg/ml of methionine. A multianalogue-resistant mutant of Corynebacterium lilium resistant to ethionine, norleucine, and methionine sulfoxide yielded 2.3 g/L methionine in a 5L fermenter.Methionine production from different analogue-resistant yeasts are also reported in the late 1970s and 1980s. ° Mondal et al. have reported methionine production from methionine-analogue-resistant mutants of Brevibacterium heali. 

Kumar D, Garg S, Bisaria VS, Sreekrishnan TR, Gomes J. Production of methionine by a multianalogue resistant mutant of Corynebacterium lilium. Process Biochem 2003 38 1165-71. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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