Correlated spectroscopy HETCOR

Heteronuclear correlation spectroscopy (HETCOR) Shift-correlation spectroscopy in which the chemical shifts of different types of nuclei (e.g., H and C) are correlated through their mutual spin-coupling effects. These correlations may be over one bond or over several bonds. 

Fig. 13.8 Proton-carbon correlated spectroscopy (HETCOR) contour plot of nylon 6.

In order to remove unwanted organic peaks in the proton spectra, one has to resort to 2D H- P heteronuclear correlation spectroscopy (HETCOR). When performed via CP, HETCOR sees only protons capable of pro-... 

Heteronuclear correlation spectroscopy (HETCOR or C-H HETCOR) (Section 9.12) A two-dimensional NMR method used to display the coupling between hydrogens and the carbons to which they are attached. 

D NMR techniques like correlation spectroscopy (HETCOR, COSY) and J-resolved experiments (Off-MAS, slow spinning MAS), which play a significant role in the detailed characterization of the structure of an... 

Connectivity is disclosed even more powerfully by heteronuclear correlation spectroscopy (HETCOR). Here, an H NMR spectrum is juxtaposed with a C spectrum. This allows the mapping of a molecule along its entire C-H framework by revealing the identity of C-H bonded fragments. The principle is illustrated again with l-bromopropane in the spectrum shown below. 

The hydroformylation of an unsaturated steroid proceeded in high chemo-, diastereo-, and regioselectivity (Scheme 14.9) with diastereoselectivity assigned by correlation spectroscopy (COSY), and heteronuclear correlation spectroscopy (HETCOR) spectra." This reaction of this trisubstituted alkene used a [Rh(nbd)Cl]2 precursor (nbd) and P( -Bu)3 as a ligand, at 120°C and pressures of 100-120 bar. 

Two-dimensional NMR analysis (COSY and heteronu-clear correlation spectroscopy [HETCOR]) was performed to make the complete H and C NMR assignment for a-, (3-, 7-, and 8-tocopherol, as well as for the acetate and hemisuccinate of a-tocopherol. C NMR was found to be especially useful for distinguishing between the various tocopherols and between natural D-isomer and the DL-racemic mixture. High-resolution NMR allows for the quantitative determination of a mixture of the four diastereomeric pairs in racemic a-tocopherol. ° ... 

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