Cornu cells

CORNU A, BESLE J M, MOSONi p, GRENET E (1994) Lignin-carbohydrate complexes in forages structure and consequences in the ruminal degradation of cell-wall carbohydrates. Reprod Nutr Dev. 34 385-98. 

FIGURE 26-5 Immunohistochemical localization of type I corticosteroid receptor (mineralocorticoid receptor) in the rat hippocampus. (A) Mineralocorticoid immunoreactivity is concentrated in pyramidal cell fields of the cornu ammonis (CA2). (B) High-power photomicrograph shows that steroid-bound mineralocorticoid receptors are primarily localized to neuronal cell nuclei. (Courtesy of Dr James P. Herman, Department of Anatomy and Neurobiology, University of Kentucky.)... 

Fig. 19 Staining for BrdU in CA1 of short-term (A) and long-term (B) monkey groups. Note the marked increase of positive cells after ischemia and their homogeneous distribution between pyramidal and radiate cell layers. A monkey not injected with BrdU served as a negative control (-). The position of the visual field within cornu Ammonis corresponds to the middle portion of CA1 as shown in Fig. 3A). Scale bar= 100 pm...

Fig. 20A, B Statistical analysis of the density of BrdU+ cells in cornu Ammonis. A In the short-term survival group after BrdU the density peaked in the second postischemic week (days 9 and 15). B In long-term monkey group the density was significantly higher in postischemic compared to control brains. p< 0.05, p<0.01, p< 0.001, one-way AN OVA followed by Tukey-Kramer post hoc...

Fig. 23A-E (on page 41) Long-term fate of BrdU+ cells in cornu Ammonis (for all images, BrdU is shown in the left panel). A Rod-shaped Ibal+ microglia express BrdU in postischemic day-79 CA1 (arrows). B A few oligodendrocytes positive for CNP also colabeled with BrdU in the postischemic monkeys (micrograph from day-79 CA1). C Lack of colabeling of BrdU (arrows) with /3111-tubulin (day-44 CA1). D Lack of colabeling of BrdU (arrowheads) with NeuN (arrows) (day-44 CA1). E A cell that is positive for BrdU and Hu in CA4 (postischemic day 23) is depicted by arrows and shown in channel separation and orthogonal projections in the lower panel. Scale bars = 10 pm (A, B, E) 20 pm (C) 50 pm (D)...

Table 11 Approximate proportions of various de novo-generated cell phenotypes in several regions of adult monkey forebrain after ischemia (long-term survival animals). Note that outside the germinative centers DG and SVZa, the most common proliferating cells were microglial cells followedby astrocytes. BrdU+/Musashil+/GFAP cells in parenchyma were considered putative local progenitors (see text for details). Note that such cells were absent in cornu Ammonis...

Most studies of overall cell density have reported no significant change in schizophrenia (Dwork, 1997 Harrison, 1999 Arnold, 2000). Two studies provided estimates of total hippocampal cell number and found no changes in any of the four sectors of the cornu ammonis in schizophrenia (Heckers et al., 1991 Walker et al., 2002). The finding of normal total cell number is important for the interpretation of decreased hippocampal volume reported by neuroimaging studies of patients with schizophrenia. In contrast to neuropsychiatric disorder such as temporal lobe epilepsy and dementia, smaller hippocampal volume is not the macroscopic correlate of pyramidal cell loss in schizophrenia. 

Figure 6.1. Schematic drawing by Ramon y Cajal (1911) of tire main cells, connections and flow of impulse traffic in tlie hippocampus. Alv alvus, CA Cornu Ammonis, DG dentate gyi us, EC entorhinal cortex, MF mossy fibers, PP perforant patli, Sch C ffer collaterals. Sub subiculum...

A. Ferster, C. Vermylen, G. Cornu, et al. Hydroxyurea for treatment of severe sickle cell anemia a pediatric clinical trial. Blood 88, 1960 (1996). 

VAILHE, M.A.B., MIGNE, C., CORNU, A., MAILLOT, M.P., GRENET, E., BESLE, J.M., ATANASSOVA, R., MARTZ, F., LEGRAND, M., Effect of modification of the 0-methyltransferase activity on cell wall composition, ultrastructure and degradability of transgenic tobacco, J. Sci. Food Agric., 1996, 72, 385-391. 

Besle, J.M., A. Cornu and J.P. Jouany, 1994. Roles of structural phenylpropanoids inforage cell wall digestion. J. Sci. FoodAgrio. 64, 171-190. 

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