Corneal copper deposits

Orlin A, Orlin SE, Makar GA, Bunya VY. Presumed corneal copper deposition and oral contraceptive use. Cornea 2010 29(4) 476-8. 

Sensory systems Eyes A 23-year-old woman developed bilateral corneal opacities due to copper deposition deep in Descemet s membrane [54 ]. The serum copper concentration was 1.89 mg/1. When she stopped taking an oral contraceptive her serum copper concentration fell but the corneal deposits persisted. 

Kayser-Fleischer corneal ring (B. Kayser, 1902 B. Fleischer, 1903) occurs in Wilson s disease. It has also been observed in alcoholic liver disease. (47) Deposits of copper compounds form a brownish green comeal ring of 1 - 3 mm in width near the limbus. It can be identified at an early stage by slit-lamp examination, (s. fig. 4.17) Individual radiating, greenish brown sunflower cataracts are sporadically detectable in Wilson s disease. 

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