Copper-Catalyzed Synthesis of N,S-Heterocycles

Bonache, M.A., Gerona-Navarro, G., Martin-Martinez, M., Garcia-Lopez, M.T., Ldpez, P., Cativiela, C., and Gonzdlez-Muniz, R. (2003) Synlett, 1007-1011. 

Lopez-Perez, A., Adrio, J., and Carretero, J.C. (2009) Angew. Chem. 

Martin-Matute, B., Pereira, S.I., Pena-Cabrera, E., Adrio, J., Silva, 

Sundbeig, R.J. (1984) in Comprehensive Heterocyclic Chemistry, vol. 4 (eds A.R. Katritzky and C.W Rees), Pergamon Press, Oxford, pp. 313-376. 

Transition metal-catalyzed activation of C-H bonds has made significant progress, the applications of which have received growing efforts to the construction of various heterocycle units relevant to natural products, pharmaceuticals, and materials. However, the majority of these currently available C-H bond activation transformations require noble transition metal catalysts, typically including palladium, rhodium, or ruthenium. Therefore, the development of green, sustainable, and economical transition metal catalysts for the catalytic C-H activation is one of the major challenges. 

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