Copper aldimines conjugate additions

Activation by TMSCl has also been applied to the allylstannane allylation of aldimines ", the copper-catalysed conjugate addition of organoaluminium reagents to enones, and in the uncatalysed conjugate addition of organozincs in THF/iV-methylp3Trofidone. Its involvement in the conjugate addition of stabilized... 

Except for the well-documented conjugate additions of diethylaluminum cyanide,92 triethylaluminum-hydrogen cyanide and Lewis acid-tertiary alkyl isonitriles,93 examples of Lewis acid catalyzed conjugate additions of acyl anion equivalents are scant Notable examples are additions of copper aldimines (233),94, 94b prepared from (232), and silyl ketene acetals (234)940 to a,(3-enones which afford 1,4-ketoal-dehydes (235) and 2,5-diketo esters (236), respectively (Scheme 37). The acetal (234) is considered a glyoxylate ester anion equivalent. 

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