Conveyance of Quartz Dust to Other Organs

Dorentrup quartz powder causing fatal acute silicosis a 25-years-old woman packing scouring powder for 2 /2 years induced miliary hepatic granulomas composed of macrophages containing crystalline siUca (Giese 1931). 

In a miner aged 51 years exposed to silica dust for 5 years and 10 months, who died 20 years later, Ni-COD (1950) found small silicotic nodules rich in macrophages in the white pulp. 

In a case of asbestosilicosis of the lung Goldberg (1961) did not find any asbestos bodies in the spleen, but the lymphatics of trabelular arteries and veins contained brown particles which were bire-fringent, being likewise probably silica particles. 

In the bone marrow of Valais miners all stages of silicotic lesions from a simple accumulation of dust-laden macrophages to fibrotic nodules were described (Nicod and Gardiol 1960). 

Phagocytosis of particulate air pollutants by human alveolar macrophages stimulated the bone marrow (Mukae et al. 2000). 

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