Convergent Biosciences

Convergent Bioscience iCE280 Isoelectric focusing Whole capillary imaging... 

Convergent Bioscience has an interesting approach to detection in CE by using a CCD (charge-coupled device) camera to image the entire capillary (Figure 7). A UV-transparent capillary is needed and the entire capillary is excited with a xenon lamp. This is useful in cIEF... 

FIGURE 7 Schematic of a whole capillary-imaged CE instrument. Drawing courtesy of Kevin Daniel O Flaherty and Christopher James O Flaherty (adapted from the Convergent Bioscience Web site, www.convergentbiosci.com). 

The CFR 21 part 11 compliant software newly released by Convergent Bioscience makes imaged cIEF a viable technique for use in QC environments for release testing of therapeutic proteins or antibody molecules. i-cIEF has also been used heavily for characterization of protein modifications such as deamidation and isomerization, as well as oligosaccharide structure analysis. ... 

H.T. Huynh, J.J. Kim, and Y. Won, DNA Microarray Classification with Compact Single Hidden-Layer Feedforward Neural Networks . Proc. Frontiers in the Convergence of Bioscience and Information Technologies (FBIT 2007), Cheju Island, Korea2008 pp. 193-198. 

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