Connectivity search

Try to find signals suitable as entering points for subsequent signal assignments. Check the spectrum to establish first J-connectivities. Search for identical J-splittings in the case of simple spectra and/or search for characteristic distortions of line intensities (well known in it.s simplest form for AB-spectra). 

Connectivity search A search (by computer) for crystal structures containing atoms that are connected together in a manner defined by the input to the search program. 

Signature library Disease-drug connectivity search... 

Figure 1.6 The top section of the search tree explored by 3DSEARCH to identify four water molecules arranged in a hydrogen-bonded ring. Shaded nodes in the search tree denote results obtained from a full substructure or connection search. Unshaded nodes denote results that have been recycled. All nodes in the bottom half of the search tree (not shown) are unshaded. A final rapid step (Step 4 in Figure 1.5) checks for a connection between the first and last identified water molecules. Reproduced from [32] by permission of the International Union of Crystallography...

All Harvester pages are indexed from Google and other search engines as well. A search term in combination with the words bioinformatic harvester retrieves the corresponding Harvester pages. However, it should be noted that Google is not well suited for long lists of search terms as it always uses the AND operator to connect search terms. 

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