Conjugated Alkene Hydrogenation Investigated in Micro Reactors

3 Conjugated Alkene Hydrogenation Investigated in Micro Reactors Cas/liquid reaction 19 [CL 19) Hydrogenation of Z-(a)-acetamidocinnamic methyl ester 

By homogeneous reaction of the conjugated double bond system selectively the C=C double bond is hydrogenated [63-66] the ester function is not affected. Moreover, by action of the chiral catalyst, a chiral hydrogenated product is created with good enantioselectivity. 

The catalyst was of Rh/diphos type, using as diphos ligands sulfonated (S,S)-1,2-bis(diphenylphosphanylmethyl)cyclobutane and sulfonated (2S,4S)-2,4-bis(diphenyl- 

Kinetic constant - activation energy - benchmarking to mini batch 

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