Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Conjugate hydroxyl-directed

Natural polyketide macrolides cpothiloncs A and B were synthesized via a diastereoselective hydroxyl directed nitrile oxide cycloaddition and a new chemoselective protocol for isoxazoline reduction <01JOC6410, 01JA3611>. In particular, Mg(ll) directed 1,3-DC of nitrile oxides with chiral allylic alcohols 56 could be used to generate isoxazolines 57 in a high selective fashion <01AG(E)2082>, and conjugate A -isoxazolines, such as 58,... [Pg.239]

Hydroxylation of 711 at C-2 can be achieved by an intramolecular conjugate addition of the benzamide to the enone system. The reaction takes place in high yield in the presence of a Lewis acid and affords direct hydroxylation with a syn relationship to the amide group via an intermediate 1,3-oxazoline (Scheme 7.223). " ... [Pg.274]

See other pages where Conjugate hydroxyl-directed is mentioned: [Pg.62]    [Pg.827]    [Pg.120]    [Pg.71]    [Pg.119]    [Pg.219]    [Pg.51]    [Pg.312]    [Pg.419]    [Pg.339]    [Pg.224]    [Pg.42]    [Pg.759]    [Pg.843]    [Pg.874]    [Pg.249]    [Pg.25]    [Pg.843]    [Pg.654]    [Pg.45]    [Pg.161]    [Pg.278]    [Pg.33]    [Pg.20]    [Pg.49]    [Pg.195]    [Pg.563]    [Pg.869]    [Pg.945]    [Pg.363]    [Pg.272]    [Pg.192]    [Pg.1046]    [Pg.134]    [Pg.240]    [Pg.111]    [Pg.144]    [Pg.953]    [Pg.50]    [Pg.56]    [Pg.41]    [Pg.175]    [Pg.88]    [Pg.953]    [Pg.645]    [Pg.228]    [Pg.103]    [Pg.30]   
See also in sourсe #XX -- [ Pg.393 ]



SEARCH



Conjugate hydroxylation

Direct conjugation

Directivity hydroxyl

© 2024 chempedia.info