Conformations molecular chaperones role

Molecular chaperones are proteins that have been said to play a role in the maintenance of conformation, stability, and function of the client protein within the cell. Heat-shock protein 90 (Hsp 90) is an ATP-dependent molecular chaperone that has several oncogenic client proteins involved in signal transduction, cell cycle regulation, and apoptosis, and has recently become a focus of interest as potential anticancer drug target. 

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