Conformational Analysis on Small Data Sets

Yoshii et al. (2001) have re-examined the conformers of Lilial and its corresponding benzoxepin derivative (40a). When the f-butyl group and 

1-Methyl-3-(2-methylpropyl)cyclohexanol was conveniently prepared in the laboratory in two steps 1,4-conjugate addition of Ao-butyl 

Following the exciting discovery of 1-methyl-3-(2-methylpropyl)cyclo-hexanol, we synthesised over 25 analogues to investigate the effect of the alkyl substitution pattern and ring size on the odour properties of 

Column CP-Chirasil-Dex CB, dimensions 25mxO.25mmxO.25Tm  

R4 and R5 independently are H or Me R3 = /-butyl, s-butyl, /-butyl, cyclohexyl, /-amyl the alkyl group can also contain unsaturation. 

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