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Conclusion Perspectives

As with most things related to p53, each additional piece of information pertaining to control of its degradation alerts us to the complexities of regulating this guardian of the genome . [Pg.83]

We wish to thank Rachael Klevitt, Peter Brzovic, Cyril Dominguez, Rolf Boelens and R. Andrew Byrd for their assistance in analyzing E2-E3 structural data. [Pg.84]

Heeshko, a. and A. Ciechanovee, The ubiquitin system. Annu Rev Biochem, 1998, 67, 425-79. [Pg.84]

Weissman, a. M., Themes and variations on ubiquitylation. Nat Rev Mol Cell Biol, 2001, 2(3), [Pg.84]

PiCKAET, C. M., Mechanisms underlying ubiquitination. Annu Rev Biochem, 2001, 70, 503-33. [Pg.84]

In conclusion, perspective directions for investigation of PVD-produced composite films with M/SC nanoparticles and possible areas for their practical applications are presented. [Pg.524]

An example the hippocampus in Alzheimer s disease The mechanistic aim of pharmacology Hippocampus-specific endpoints Choice of representative subjects Conclusion Perspectives... [Pg.2]

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