Concerted transition model application

For the allosteric model based on a concerted transition between the two conformational states, as considered here in the model for glycolytic oscillations, application of definition (2.27) in the case where the two states of the enzyme differ only by the affinity toward the substrate (0 = 1) leads to expression (2.28) for the Hill coefficient related to saturation of the enzyme by the substrate (Goldbeter, 1976,1977) ... 

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