Complex Systems and Applications

At present, the association constants of single host-guest complexes may be measured with the help of atomic force miCToscopy (AFM) force spectroscopy. For this purpose, the host must be immobilized on a gold surface, and the guest must carry one additional 

The binding of C-3 by a simple caUx[4]arene host in nonpolar media can be improved by a factor of 25 by the formation of host clusters on the surfaces of gold nanoparticles. Applications of host-guest complexes are mainly directed towards the development of sensors. For example, acetylcholine detection at micromolar concentration is based on inclusion of a fluorophore containing the pyridinium unit (tranj-4[4-(dimethylamino) 

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Hulin B, Tschachtli R. Identifying software hazards with a modified CHAZOP. PESARO 2011 the first international conference on performance, safety and robustness in complex systems and applications. Munich, Germany 2011. 

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