Comparison of Resting and Operational Stability

Discussion of the concepts of resting and operational stability raises the question of their comparability and mutual convertibility. This subject has been discussed by Yamane et al. (Yamane, 1987). The validity of Eq. (5.74) for the description of enzyme deactivation is assumed. 

In summary, the results are quantified in Table 5.4 and are summarized as follows  

Under conditions of dominant pore diffusion (rj = 1/cp 1), the apparent (but not the actual ) half-life is always longer than that measured with native enzyme (where T) = 1). The result depends on the reaction order, initial degree of conversion, and operational policy. 

Kinetics, Diffusion Continuous stirred tank reactor (CSTR) Plug-flow reactor (PFR)  

Flow rate Q = const. = constant flow rate policy  

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