Comparison of Reagents in Phosgenation Reactions

Each of these criteria is determined by its intrinsic value, although among several criteria, one leading criterion generally predominates. Nevertheless, by adjusting the criteria with respect to each other, the optimal phosgenation reagent can be 

In the following, the same or similar phosgenation reactions with various phosgenation reagents are compared with regard to certain criteria. They are presented in the order of Chapter 4. 

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Comparison of Reagents in Phosgenation Reactions 605 MBOA, 6-methoxy-2-oxo-2,3-dihydrobenzoxazole 12... 

Yield is still the primary criterion in chemistry because, indirectly, it contains some other preparative criteria such as reactivity and selectivity, and also has a significant bearing on costs. Therefore, yield will be the leading criterion in our comparison of same and similar reactions accomplished with various phosgenation reagents. Further criteria to be taken into consideration are purity, handling, and work-up, as well as safety, toxicity, and environmental impact. 

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