Column evaluation pore size distribution

The silica-based SEC packings which are currently being employed were Introduced on the market in 1980 and there has since been very little improvement In their properties in terms of pore size distribution, particle size etc. Now, initiated by theoretical Investigations of the resolution of SEC columns, a new family of SEC packings Is beginning to be produced and marketed. The new packings are characterized by a particle size smaller than 5 / m, adequate porosity, and superior bonding chemistry. The Bio-Series 6F 250 column from DuPont de Nemours Is a typical example. However, the performance - with reference to resolution, analysis time and peak capacity — of this novel material has not yet been evaluated. 

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