Cobalt reaction with phenyl halides

Finally, some successful reductive arylations have been reported via reaction of aryl halides with cobalt(I) nucleophiles. Generally speaking these reactions are only successful when the aryl hahde has an electron-withdrawing substituent and yields are generally less than 15% [58,59]. Thus, pyridinecobaloxime(I) reacts with p-bromoacetophenone, methyl-m- and methyl-/)-bromobenzoate, and p-bromo-a,a, -trifluorotoluene, to produce the expected substituted phenyl(pyridine)[Pg.441]

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