Cobalt catalyzed decarbonylation

Scheme 8.15 Cobalt-catalyzed decarbonylation of aryl substituted 1-propanols.

For a few combinations of less reactive dienes and dienophiles, transition metal catalyzed variants of the Diels Alder reaction have been developed. An example is the cycloaddition of an unpolar diene and an unactivated alkyne however, except when the reaction is catalyzed with iron, nickel, cobalt, or rho-dium(I) complexes, the temperature required often causes competing decomposition, even for the intramolecular version. [2] Wilkinson s catalyst [3] - tris(triphenylphosphane)rho-dium(I) chloride - frequently used for hydrogenations and for decarbonylations, permits the cyclization of 4 to the annelated cyclo-hexadiene 5 in excellent yield in only 15 minutes at 55 °C in trifluoroethanol as solvent (Scheme 2). [2c]... 

ACS are present in methanogens, acetogens and carboxydotrophic microorganisms where they catalyze the synthesis and/or the decarbonylation of acetylCoA according to the following reaction, where CoFeS correspond to a correnoid/cobalt containing iron-sulfur protein [158, 165]. 

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See also in sourсe #XX -- [ ]

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