Clomipramine for obsessive-compulsive disorder

TABLE 13-13. Selective serotonin reuptake inhibitors versus clomipramine for obsessive-compulsive disorder... 

Koran LM, McElroy SL, Davidson JRT, et al. Fluvoxamine versus clomipramine for obsessive-compulsive disorder a double-blind comparison. J Clin Psychopharmacol 1996 16 121-129. 

Feinberg M. Clomipramine for obsessive-compulsive disorder. Am Fam Physician 1991 43 1735-8. 

Although several antidepressants are EDA-approved for use in children, only one, fluoxetine, is currently approved for childhood depression. Imipramine is approved for the treatment of enuresis, clomipramine for obsessive-compulsive disorder in children 12 years and older, and fluvoxamine along with fluoxetine is approved for obsessive-compulsive disorder in children. The treatment of depression in children remains challenging, as depression can be difficult to diagnose and treat once identified. The studies involving imipramine, sertraline, and fluoxetine found that the dose range and titration as well as adverse effects were similar to those in adults. " ... 

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