CLIP domain, function

Figure 12.7 AhR surrogate with a bound aza-PAH as generated by Quasar. For clarity, the front section has been clipped. Areas colored in gray/brown represent hydrophobic properties areas in green H-bond donor functions areas in yellow indicate H-bond acceptors and purple domains correspond to H-bond flip-flops. No salt bridges are observed in this model as the ligands lack any charged groups. See color plates.

Feierbach, B., E. Nogales, K. H. Downing, and T. Stearns (1999). Alflp, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin./ Cell. Biol. 144, 113-124. 

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