Cleidocranial dysostosis

An examination of McKusick s book reveals some candidates achondroplasia, Apert s syndrome, Cruzon s disease, polydactyly, syndactyly, cleidocranial dysostosis, and possibly others. But several of the above list do not meet all the criteria, and none is absolutely foolproof. Achondroplasia is perhaps best, but I am told that diagnosis in infancy is by no means obvious in all cases. 

Congenital pseudoarthrosis of the clavicle may he mistaken for a fracture. This condition is almost always right sided and rarely hilateral. It usually presents with a painless, palpable prominence in the mid-portion of the clavicle. Approximately half of all patients present in the first 2 weeks of life, the others during childhood. The differential diagnosis includes cleidocranial dysostosis or a birth injury. Radiographically there is a defect in the middle segment of the clavicle, and the ends of the bones are... 

---