Classification of indicators

There is a large body of literature on assessment of the therapeutic benefit of AEDs, mostly composed of comparative clinical trials. A few meta-analyses have been performed. For any given AED, it is sometimes difficult to formulate an opinion due to the different methodologies used for assessment tested alone or as an add-on drug, wide range of dosages, different types of seizures or epileptic syndromes. Classifications of indications and recommendations for use vary accordingly. 

---