Cipramil Citalopram

The FDA approval of citalopram (Cipramil) provides a convenient example of how this works. Seven placebo-controlled efficacy trials were conducted. Two showed small but significant differences between drug and placebo. Another two trials failed to show significant differences, but were deemed too small to count. Three other trials that were deemed... 

The author of the FDA memo revealing the decision to hide the existence of the clinical trials that had failed to find a difference between drug and placebo was Dr Paul Leber, Director of the FDA Division of Neuropharmacological Drug Products. Here is what he wrote about the labelling of Cipramil, which is referred to by its generic name, citalopram, in the document ... 

Citalopram (Celexa / Cipramil) and Escitalopram (Lexapro / Cipralex) Zopiclone (Imovane) and Eszopiclone (Lunesta)... 

Celexa Cipramil Citalopram hydrobromide EINECS 261-890-6 HSDB 7042 Lu 10-171-B. A serotonin uptake inhibitor. Antidepressant. Crystals mp= 182-183°. KefalasA/S. 

Cipramil (Citalopram hydrobromide). Lundbeck Ltd. UK Summary of product characteristics, January 2007,... 

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