Sevoflurane Cisatracurium

Wulf H, Kahl M, Ledowski T. Augmentation of the neuromuscular blocking effects of cisatracurium during desflur-ane, sevoflurane, isoflurane or total i.v. anaesthesia. Br J Anaesth 1998 80(3) 308-12. 

Both desflurane and sevoflurane significantly increase the neuromuscular blocking effects of rocuronium compared with isoflurane or propofol (41,42). The effective doses of rocuronium for 50% depression of single twitch height were 95,120,130, and 150 pg/kg for desflurane, sevoflurane, isoflurane, and propofol respectively. There were no differences in recovery profiles between the four drugs using equieffective doses. Desflurane, sevoflurane, and to a lesser extent isoflurane, also potentiated the neuromuscular blocking effect of cisatracurium by 30% compared with propofol (43,44). 

Baraka AS, Taha SK, Kawkabani NI. Neuromuscular interaction of sevoflurane - cisatracurium in a myasthenic patient. Cm JAnesh (2000) 47,562-5. 

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