Cirrhosis Child-Pugh classification

Liver Disease — The oral Cl of LTG is 1/2 to 1/4 the Cl of inpatients with moderate to severe hepatic cirrhosis (Childs-Pugh classification of B or C, respectively) compared to healthy control subjects. 

The Child-Pugh classification system uses a combination of physical and laboratory findings to assess and define the severity of cirrhosis and is a predictor of patient survival, surgical outcome, and risk of variceal bleeding (Table 21-3). 

Albers I, Hartmann H, Bircher J, Creutzfeldt W (1989) Superiority of the Child-Pugh Classification to quantitative fiver function tests for assessing prognosis of liver cirrhosis. Scand J Gastroenterology 24 269-276... 

Korner, T., Kropf, J., Kosche, B., Kristahl, H., Jaspersen, D., Gessner, A.M. Improvement of prognostic power of the Child-Pugh classification of liver cirrhosis by hyaluronan. X. Hepatol. 2003 39 947-953... 

Tab. 35.6 Classification of hepatic cirrhosis according to Child-Turcotte (1964) and Pugh (1973) (stage A = good compensation, stage B = significant functional loss, stage C = decompensation) Quick s value is additionally used by Pugh (INR = international normalized ratio)...

Various indices have been developed using weighted parameters to calculate the probability of fatality or survival in the individual case. Classification of cirrhosis according to the criteria devised by Child and Turcotte (1964) and the modification established by Pugh (1973) has been widely accepted. Our experience shows that the additional use of the GEC and the ICG test makes the classification more reliable, particularly in stages A (= score 5-7) and B (= score 8-10). (s. tab. 35.6)... 

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