Chylomicrons adipose tissue, regulation

Figure 6-9. Regulation of triacylglycerol stores in adipose tissue. Left = in the fed state. Right = in the fasted state. TG = triacylglycerol FA = fatty acid LPL = lipoprotein lipase DHAP = dihydroxyacetone phosphate = stimulated by circled TG = triacylglycerol of chylomicrons and VLDL.

C-III, and phospholipids are transferred to EfDL. Apolipoproteins E and C-II are transferred to chylomicrons from EfDL and evenmally back through these metabolic events. Hepatic VLDL synthesis is regulated in part by diet and hormones and is inhibited by uptake of chylomicron remnants in the liver. VLDL is secreted from the Ever and serially converted via LPL to intermediate-density hpoprotein (IDL) and finally to LDL. VLDL receptors are found in adipose tissue and muscle and bear close homology to the structure of LDL receptors. 

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