Serum cholesterol

Serum cholesterol Serum Quail Yes Decreased Leonzio and Monaci (1996)... 

Perhaps the most hopeful sign of progress is the belated recognition of "paradoxical" reactions to the lipid-lowering diets that have been widely used for decades. For example, researchers at the South-Western Medical Center in Dallas repeatedly find "marked individual variations in response to the diet." In many persons these diets show little benefit, or increase LDL cholesterol, serum triglycerides, or... 

Water soluble, high viscosity grade cellulose ether compositions are useful for the reduction of serum lipid levels, particularly total serum cholesterol, serum triglycerides and low density lipoprotein (LDL) levels, and/or attenuate the rise of blood glucose levels. The compositions may be in the form of a prehydrated ingestible composition, e.g. a gelatin, or a comestible, e.g. a biscuit. 

In contrast to its effects on glucose metabolism, tacrolimus offers potential advantages over ciclosporin for lipid disorders (1101). Compared with ciclosporin-based immunosuppressive regimens, total cholesterol and LDL cholesterol serum concentrations were lower in patients taking tacrolimus for 1 year (1102). Both findings were considered to result from a significant glucocorticoidsparing effect of tacrolimus. 

Rabbits fed a 0.5% cholesterol diet had atherosclerotic plaques on over 50%i of the aorta surface whereas the 0.5% cholesterol plus 40 mg lignan complex/kg body/per day reduced atherosclerosis by 34.4% (Prasad, 2005). Furthermore, the added lignan complex lowered the total cholesterol, LDL cholesterol, serum, and aortic malondialdehyde by 20%, 14%, 35%, and 58%, respectively. Unlike previous studies, the lignan enhanced HDL cholesterol by 25% and 30% in normocholesterolemic and hypercholesterolemic rabbits, respectively. Slightly higher (33% and 35%) reductions in total cholesterol and LDL cholesterol, respectively, were observed in rabbits on a 1% cholesterol diet containing 15 mg SDG/kg/day (Prasad, 1999). A 73% reduction in atherosclerosis was observed in the rabbits given the SDG diets compared to the 1% cholesterol diets. 

Maintenance of normal bowel habits, lower blood pressure, and lower cholesterol serum concentrations have been attributed to adequate dietary fiber intake. Some evidence, although inconclusive, also suggests that fiber has a role in the prevention of colon cancer and... 

Contaminated Fish Consumption. Serum cholesterol, serum GGT, and blood pressure, but not serum HDL cholesterol or triglycerides, were positively correlated with serum PCB levels in 458 residents of Triana, Alabama (Kreiss et al. 1981). These associations were independent of age, sex, fish consumption, body mass index, and alcohol consumption. Consumption of contaminated fish was the only known source of PCB exposure, but PCB intake was not estimated. DDT was also increased in the serum of the people and in the fish, and serum DDT and serum PCB levels were highly correlated. 

Serum DDT levels did not contribute to the variance in serum cholesterol, serum GGT, or blood pressure. 

At blood levels of from 0.06 to 0.20 mg selenium/L, Deguchi (1985) found selenium to be positively correlated with grasping power and blood pressure in normal men and women and with hematocrit and hemoglobin concentrations in normal women. Similar correlations were not found in subjects with proteinuria or hypertension. In addition, Gebre-Medhin et al. (1988) found that in healthy children, serum selenium levels of 0.055-0.082 mg selenium/L were positively correlated with serum cholesterol, serum triglycerides, low and very low density lipoproteins, and apolipoproteins. Similar correlations were not found in diabetic children, who have slightly elevated serum selenium levels. 

Lind, B. M., R. Littbarski, G. Hohlbach, and K. O. Moller. 1990. Long-term investigations of serum cholesterol, serum triglyceride and HDL cholesterol in heritable hyperlipidemic rabbits. Zeitschriftfilr Versuchstierkunde 33 245-249. 

Wichlinski LM, Sieiadzki E, Gruchala M Correlaticxi between the total cholesterol serum con-centiation data and carbamazepine steady-state blood levels in humans. Drug Intell Clin P/iami (1983) 17, 812-14. 

Liver weight (g/100 g) Serum cholesterol Serum triglyceride Cholesterol oxidation ... 

Berkowitz, D. The effects of Atromid on serum cholesterol, serum triglycerides, and radioactive fat tolerance in patients with hyperlipidemia. A preliminary report. J. Atheroscler. Res. 3, 538 (1963). 

Table III. Levels of Liver Cholesterol, Serum Cholesterol, TG and FFA in...

The first patient described by Kelley et.al.(l) also had an abnormal lipoprotein pattern consistent with Type II hyperlipo-proteinaemia. No other family member even those with reduced APRTase deficiency had Type II hyperlipoproteinaemia. In the present family the serum cholesterol serum triglycerides and lipoprotein pattern were determined and were normal for the propositus and her mother. However her father who had normal APRTase activity had an elevated concentration of serum triglycerides and showed a raised pre-3 band both characteristic of T3 e IV hyperlipoproteinaemia. There is thus no essential association between APRTase deficiency and a disorder of lipoprotein metabolism, since they occur independently in the present kindred. 

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