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Chlorzoxazone 6-hydroxylation

Kim RB, O Shea D, Wilkinson GR. Interindividual variability of chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms. Clin Pharmacol Ther 1995 57 645-655. [Pg.623]

Yamazaki H, Guo Z, Guengerich FP. Selectivity of cytochrome P4502E1 in chlorzoxazone 6-hydroxylation. Drug Metah Dispos 1995 23 438 140. [Pg.637]

Burckart GJ, Frye RF, Kelly P, et al. (1998) Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6-hydroxylation. Clin Pharmacol Ther 63 296-302. [Pg.131]

Inoue, R., H. Yamazaki, and T. Shimada (2000). Characterization of liver microsomal 7-ethoxy-coumarin 0-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 gene. Arch. Toxicol. 74, 372-378. [Pg.491]

E1 Chlorzoxazone 6-hydroxylation" p-Nitrophenol hydroxylation"" iV-N itrosodimethylamine A -demethylationP Ethanol Isoniazid 4-Methylpyrazole "" Diethyldithiocarbamate"" Chlorzoxazone... [Pg.621]

Figure 4 Effects of OPZ, l,2-dithiole-3-thione (D3T), and OPZ M3 on CYP-catalyzed activities in Escherichia coli membranes. CYPl Al, 1A2, and IBl activities were estimated by 7-ethoxyresorufin 0-deethylation, CYP3A4 activity by testosterone 6p-hydroxylation, and CYP2E1 by chlorzoxazone 6-hydroxylation. (From Ref. 64.)... Figure 4 Effects of OPZ, l,2-dithiole-3-thione (D3T), and OPZ M3 on CYP-catalyzed activities in Escherichia coli membranes. CYPl Al, 1A2, and IBl activities were estimated by 7-ethoxyresorufin 0-deethylation, CYP3A4 activity by testosterone 6p-hydroxylation, and CYP2E1 by chlorzoxazone 6-hydroxylation. (From Ref. 64.)...
E1 Liver, lung, other tissues ER Chlorzoxazone 6-hydroxylation... [Pg.525]

See other pages where Chlorzoxazone 6-hydroxylation is mentioned: [Pg.926]    [Pg.218]    [Pg.264]    [Pg.266]    [Pg.270]    [Pg.273]    [Pg.273]    [Pg.275]    [Pg.325]    [Pg.556]    [Pg.731]    [Pg.926]    [Pg.467]    [Pg.651]    [Pg.526]    [Pg.86]    [Pg.95]   
See also in sourсe #XX -- [ Pg.273 ]



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Chlorzoxazone

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