Chlorpropamide

Chlorpropamide. Chlorpropamide (l-[(p-chlorophenyl)sulfonyl]-3-propylurea), mol wt 276.75, is a white, crystalline powder, having a slight odor, mp 127—129°C. It is sold as Diabinese, is soluble in water at pH 6 (2.2 mg/mL), and practically insoluble at pH 7.3, soluble in alcohol, and sparingly soluble in chloroform, ether, and benzene. [Pg.342]

Facial dushing after ingestion of alcohol occurs in up to one-third of patients taking chlorpropamide. The mechanism, like that of the disulfiram reaction, probably involves inhibition of the oxidation of acetaldehyde, a metaboUte of ethanol. The plasma concentration of chlorpropamide may be correlated with chlorpropamide—alcohol dushing. [Pg.342]

Chlorobenzaldehyde Chlormezanone Chlorobenzene Methixene HCI p-Chlorobenzene sulfonamide Chlorpropamide... [Pg.1621]

Dyazide - Hydrochlorothiazide Dyazide - Triamterene Dycill Dicloxacillin sodium Dyclone Dyclonine HCI Dyflex - Dyphylline Dygratyl Dihydrotachysterol Dylate - Papaverine monophosadenine Dymadon - Acetaminophen Dymelor - Acetohexamide Dymenol Dimenhydrinate Dymoperazine - Trifluoperazine Dynalase - Chlorpropamide... [Pg.1695]

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