Chlorosilanes functional group transformation

Chlorosilanes are the most important functional silicon compounds. As described above, chlorosilanes can be used for silicon—carbon and silicon—silicon bond formation. In addition, chlorosilanes can be converted into other functional silicon compounds, such as hydrosilanes, alkoxysilanes, and aminosi-lanes. Hydrosilanes, alkoxysilanes, and aminosilanes can be transformed furthermore into other functional silicon compounds. Combination of functional group transformation and silicon-carbon and silicon—silicon bond formation of chlorosilanes are essential for the construction of organosilicon clusters. 

Several methods can be potentially used for the synthesis of functionalized symmetric stars. The chlorosilane method has been applied for the synthesis of three-arm PBd stars carrying one or two end-functional groups,70 as shown in Scheme 30. The dimethylamino end groups were later transformed to sulfozwitterions by reaction with 1,3-propane sultone. 

A variety of terminal functional groups and their chemical transformations on SAMs have been examined for example, (i) olefins—oxidation [23,24,131,132], hydroboration, and halogenation [23,24] (ii) amines—silyla-tion [145,146], coupling with carboxylic acids [22,146], and condensation with aldehydes [22,147] (iii) hydroxyl groups—reactions with anhydrides [148,149], isocyanates [150], epichlorohydrin [151], and chlorosilanes [152] (iv) carboxylic acids—formation of acyl chlorides [153], mixed anhydrides [154], and activated esters [148,155] (v) carboxylic esters—reduction and hydrolysis [156] (vi) thiols and sulfides—oxidation to generate disulfides [157-159] and sulfoxides [160] and (vii) aldehydes—condensation with active amines [161], Nucleophilic... 

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