3- Chloro-2-methylaniline

Chloro-4-methylaniline Methyl iodide Nitric acid... 

Dinitro-2-chloro-4-methylaniline. (02N)2(Cl)CgH(NH2).CH3, yel nds(from ale), mp 173° was prepd by warming 3,5-dinitro-2 -chloro-4-methyl benzoic acid azide with AcOH Ref l,p [539] Ref 5) and... 

To an oven-dried reaction vial were added 11 mg Pd(OAc)2 (0.05 mmol), 47 mg l,l -bis(di-f-butylphosphino)ferrocene (0.1 mmol), and 346 mg potassium carbonate (2.5 mmol). The vial was purged with argon. Then 123 jxL 2-chloro-4-methylaniline (1 mmol), 192 xL 1-phenyl-l-pentyne (1.2 mmol), and 2 mL NMP were added via syringe. The reaction was heated to 130°C, stirred at the same temperature and monitored by HPLC. The reaction was complete after 4 h. The ratio of the regioisomer was 91 9. The mixture... 

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