Chlordiaz epoxide

This class of compounds includes the BZDs like diazepam (Valium) and oxazepam (Serax), chlordiaz-epoxide (Librium), meprobamate (carbamate derivative), and related compounds, and buspirone (aryl piperazine derivative), which is an anxioselective drug. A miscellaneous group of drugs includes certain antihistaminic and anticholinergic drugs that are difficult to classify (e.g., hydroxyzine and buclizine). 

S.2.2.2 Barbiturates. A major event in the field was the launching of barbital (6,5-dieth-ylbarbituric acid) in 1903 and phenobarbital (5-ethyl-5-phenylbarbituricacid)in 1912. The barbiturates dominated the field for nearly 50 years, until the launch of Librium (chlordiaz-epoxide) in 1960, the first of the benzodiazepine class drugs. Benzodiazepines completely overtook the barbiturates and had become The dominant class of sedative hypnotic drugs until the launch of retrocyclic sedative-hypnotics. 

Chlordiaz epoxide A. MacDonald, A.F. Michaelis, B.Z. Senkowski Pages 15-37... 

Interfering bupivacaine, buprenorphine, buspirone, carbinoxamine, cetirizine, chlordiaz-epoxide, chlorpheniramine, clorazepate, fenfluramine, flecainide, loprazolam, metapra-mine, metipranolol, midazolam, moperone, naproxen, oxprenolol, phencyclidine, thiopental, tianeptine, triprolidine, weufarin... 

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