Chitosan/silica xerogel hybrid membrane

Fig. 21 Bone tissue and membranes 3 weeks after implantation of (a) pure chitosan membrane and (b) chitosan/silica xerogel hybrid membrane. For the histomorphometric analysis, the defect sites were observed at high magnification. The pure chitosan membrane was partially degraded and the remaining part (arrows) was surrounded by collagen fibers (blue), bone marrow, and osteocyte cells (red), as shown in (a). However, the hybrid membrane was almost completely degraded and the defect site (arrows) was replaced by a large number of collagen fibers and fresh new bone (blue), as shown in (b) [216]...

Figure 7.7 CLSM images of the cells cultured on the membranes for 5 h (a) pure chitosan and (b) the chitosan-silica xerogel hybrid.

Lee E, Shin D, Kim H et al (2009) Membrane of hybrid chitosan-silica xerogel for guided hone regeneration. Biomaterials 30 743-750... 

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