Chiral heterobimetallic yttrium

By virtue of a deep understanding of his LnM3tris(BINOLate)3 complexes (Ln = rare-earth metal, M = alkali metal) based on evidence from X-ray analysis and other experiments, Shibasaki developed chiral heterobimetallic yttrium(in) lithium(i) tris(binaphtholate) complex 22, which can promote the catal) ic enantioselective aza-Michael reaction of metho g lamine to enones in excellent yields with up to 97% ee as a Lewis-acid-Lewis-acid cooperative catalyst (Scheme 2.17). Transformation of the 1,4-adducts 23 afforded the corresponding optically active aziridines 24 in high yields. 

Scheme 2.20 Enantioselective cyano-phosphoiylation of aldehydes with the use of chiral heterobimetallic yttrium(iii) lithium(i) tris(binaphtholate).

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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