Chemotherapeutics novel classes

The purification, structure elucidation, and pharmacological studies on different classes of bioactive withanolides further validate the traditional uses of withanolide-producing plants to treat various ailments by local and traditional people. Diverse structural features, low toxicity, and novel and diverse mechanism of action make them suitable drug candidates for the treatment of various cancers and tumors. However, there is a need of extensive studies at the interface of chemistry and biology to fully explore the potent anticancer activity of withanolides, an essential step toward anticancer drug development with enhanced activity and lower toxicity, as compared to the available chemotherapeutic agents. 

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