Chemotherapeutic agents busulfan

Busulfan has been used extensively as a chemotherapeutic agent in the treatment of a variety of cancers. Busulfan is clinically successful for treating leukemia, solid tumors, and correcting hemoglobinopathies, and other inborn errors of the immune system. It is... 

The answer is b. (Hardmanr p 1241.) Busulfan is an alkylating agent that, in contrast to other alkylators, is an alkylsulfonate. Thioguanine is a purine antimetabolite. Bleomycin is classified as a chemotherapeutic... 

Busulfan is a white powder that is soluble in acetone. The powder is insoluble in water and readily hydrolyzes in water. Any environmental hazards that pose threats to the environment remain unknown. Busulfan is a pharmaceutical and is used in relatively small amounts therefore, so far it has been of little regulatory concern to the US Environmental Protection Agency. The potential threat of busulfan exposure is limited to workers involved in its manufacture, to patients receiving this agent as a chemotherapeutic regime, and to hospital personnel administering the drug to patients. 

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