Chemical assessment

Quint, M. et al. (ed.) (1995) Environmental Impact of Chemicals Assessment and Control, Royal Society of Chemistry, London. 

Concise International Chemical Assessment Documents (CICADs) are published by the International Programme on Chemical Safety (IPCS) — a cooperative programme of the World Health Organization (WHO), the International Labour Organization (ILO), and the United Nations Environment Programme (UNEP). CICADs have been developed from the Environmental Health Criteria documents (EHCs), more than 200 of which have been published since 1976 as authoritative documents on the risk assessment of chemicals. 

IPOS (1999a) Triphenyltin compounds. Geneva, World Health Organization, International Programme on Chemical Safety (Concise International Chemical Assessment Document 13). 

THE CONCISE INTERNATIONAL CHEMICAL ASSESSMENT DOCUMENT SERIES... 

Wright, Z.M., et al., Vehicle effects on the skin sensitizing potency of four chemicals assessment using the local lymph node assay. Ini. J. Cosmetic Sci., 23, 75. 

Cefic claims that polymeric materials, reaction intermediates and substances used for R D should not be subject to the REACH evaluation and authorisation process being proposed by the European Commission in its White Paper on future chemicals policy, it is briefly reported. On specific issues, Cefic wants a risk-based approach to chemicals assessment and regulation realistic deadlines for the REACH process and exemption from REACH of finished articles, so that it applies only to substances marketed as substances or as constituents of a preparation. 

The chlorinated chemicals assessed do not have the same risk profile. For the more volatile chemicals the safety margins between the actual exposure and the level at which no effect on the environment would be expected is quite high. For more persistent chemicals there is a need to look to the environmental compartment where they can be accumulated (mainly in sediments and biota). For some of these chemicals the safety margin is quite low and in worst-case situations serious effects may occur. For the very persistent, bioaccumulative and toxic chemicals (like dioxins, PCBs and DDT), acceptable environmental concentrations are so low and difficult to control that the industry is committed to reducing as far as possible releases to the environment through application of Best Available Techniques (BAT), mainly with respect to dioxins. For other chemicals (PCBs, DDT), production has already been halted for some years. 

EPA (1979) TSCA Chemical assessment series preliminary risk assessment phase i benzidine, it s congeners and their derivative dyes and pigments. US Environmental Protection Agency, Washington DC, EPA-560/11-80-019... 

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