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Chemical proteomics small molecule targets

Rix U, Superti-Furga G (2009) Target profiling of small molecules by chemical proteomics. Nat Chem Biol 5 616-624... [Pg.79]

Kley N. Chemical dimerizers and three-hybrid systems scanning the proteome for targets of organic small molecules. Chem. Biol. 2004 11 599-608. [Pg.585]

Figure 1.26 Kinase activity profile of three antileukemia drugs (imatinib, nilo-tinib, and dasatinib) that primarily inhibit the oncogenic BCR-ABL kinase. (From Rix, U. and Superti-Furga, G., 2009, Target Profiling of Small Molecules by Chemical Proteomics, Nat. Chem. Biol, 5(9) 616-24.)... Figure 1.26 Kinase activity profile of three antileukemia drugs (imatinib, nilo-tinib, and dasatinib) that primarily inhibit the oncogenic BCR-ABL kinase. (From Rix, U. and Superti-Furga, G., 2009, Target Profiling of Small Molecules by Chemical Proteomics, Nat. Chem. Biol, 5(9) 616-24.)...
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Chemical proteomics

Molecule chemical

Proteomics targeted

Target chemicals

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