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Chemical genomic profiling

Chemical genomics profiling of environmental chemical modulation of hmnan nuclear receptors. Environ Health Perspect 119 1142-1148... [Pg.372]

Chemical genomic profiling - using microarrays to determine the effects of highly specific drug-mediated kinase inhibition of gene expression. [Pg.177]

Haggarty, S.J., Clemons, P.A. and Schreiber, S.L. (2003) Chemical genomic profiling of biological networks using graph theory and combinations of small molecule perturbations. /. Am. Chem. Soc., 125, 10543-10545. [Pg.1058]

Fig. 6-23 Chemical-genomic profiling (data node networks derived from the mapping of from Ref. 82). (a) 276 unique combinations a matrix of 24 x 24 combinations of small and 24 single treatments of small-molecule molecules against a set of 10 strains of the... Fig. 6-23 Chemical-genomic profiling (data node networks derived from the mapping of from Ref. 82). (a) 276 unique combinations a matrix of 24 x 24 combinations of small and 24 single treatments of small-molecule molecules against a set of 10 strains of the...
Kuyper, H.D. Madhani, K.M. Shokat, Chemical genomic profiling to identify intracellular targets of a multiplex kinase inihibitor, Proc. Natl. Acad. Sci. [Pg.384]

Applications and Practical Examples 336 Example 1 Mitosis and Spindle Assembly 336 Example 2 Protein Acetylation 338 Example 3 Chemical-genomic Profiling 340 Future Development 344 Conclusion 347 Acknowledgments 348 References 349... [Pg.1221]

Chemical Genomic Profiling via Barcode Sequencing to Predict Compound Mode of Action... [Pg.299]

Chemical Genomic Profiling by Barcode Sequencing of Action 301... [Pg.301]

Fig. 1 Overview of the steps of chemical genomic profiling by barcode sequencing... Fig. 1 Overview of the steps of chemical genomic profiling by barcode sequencing...
Chemical Genomic Profiling by Baroode Sequenoing of Aotion 315... [Pg.315]

Do not exceed 1 % solvent in the cultures. If resources allow, plan on using multiple dose points so that a dose-dependent chemical genomic profile can be generated. Inhibition of growth by <20 % of solvent controls may still yield information given the performance of individual mutants in the pool. [Pg.316]

See other pages where Chemical genomic profiling is mentioned: [Pg.177]    [Pg.333]    [Pg.336]    [Pg.340]    [Pg.341]    [Pg.342]    [Pg.343]    [Pg.751]    [Pg.299]    [Pg.300]    [Pg.300]    [Pg.301]    [Pg.305]    [Pg.306]    [Pg.310]    [Pg.311]    [Pg.314]   
See also in sourсe #XX -- [ Pg.177 ]



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