ChemBridge database

Desai PV, Patny A, Sabnis Y, Tekwani B, Gut J, Rosenthal P, Srivastava A, Avery M. Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database. / Med Chem 2004 47 6609-15. 

FlexXd and GOLDb were used to virtually screen the ChemBridge and NCI databases (covering over half a million compounds) against the ATP phosphoribosyl transferase (HisG). Filtering for drug likeness was also used... 

MDL Information Systems, Inc., a subsidiary of Elsevier Science, Inc., also have a free Internet access to its database of commercially available substances, claimed to contain information on more than 400,000 chemicals (available from www.mdh.com No toxicity or environmental property data are given. Similarly, the ChemBridge Corp. provides a list of over available 450,000 substances to subscribers (www.chembridge.com). Russia s ChemStar Ltd. provides a similar type of database with over 500,000 compounds available (www.chemstar.ru). The list of compounds is downloadable in structure data hie (SDF) format and is being updated regularly. 

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