Charcot neuroarthropathy

Charcot neuroarthropathy (CN) is a progressive condition that affects the bones and joints of the foot. It is characterised by joint dislocation, subluxation and pathological fractures of the foot in neuropathic patients resulting in debihtating deformity [42]. The incidence of CN is reported to be around 0.1-0.5. Although diabetes is the most common cause in the Western World CN can occur in other diseases associated with peripheral neuropathy. There is no sex predilection and it can occur at any age but is more commonly seen in the fourth or fifth decades of fife and in patients with a long duration of diabetes [42]. 

Jude EB, Selby PL, Burgess J, LiUeystone P, Mawer EB, Page Sridcnohce M, Foster AV, Edmonds ME, Bolton AJM. Bisphosphonates in the treatment of Charcot neuroarthropathy. Diabetologia 2001 44(11) 2032. 

Pitocco D, Rudtolov V, Caputos, Mancin L, Collina MC, Manto A, Caradonna P, Chirlanda G. Six-month treatment with alendronate in acute Charcot neuroarthropathy. Diabetes Care 2005 5 1214-1215. 

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