Characterization from PMMA weight-average

However, such a strategy can be applied only for block copolymers. Molecular weight characterization of random amphiphilic copolymers currently poses its own analytical challenges. Giordanengo et al. [92] used a methylation reaction to transform methacrylic acid (MAA)/methyl methacrylate (MMA) copolymer samples that could not be properly ionized by MALDI into PMMA homopolymers. Weight average molecular weight (MJ parameters of the copolymers were then derived from values obtained for the methylated MAA-MMA molecules by MALDI, which were also validated by NMR. 

---