Chaperones consensus sequences

Fig. 3. Periplasmic pilus chaperone consensus sequence. Amino acid sequence of the PapD chaperone (top line) and consensus sequence derived from the comparison of twelve chaperones (second line). Amino acids are indicated using the one-letter code. In the consensus sequence, a letter shows a residue that is present in at least eight out of twelve sequences, an asterisk designates an invariant residue, and a box shows a position with a hydrophobic residue in all twelve periplasmic chaperones. The arrows underneath the sequence represent the /3 strands found in the PapD structure.

Fig. 2. Ribbon model of the three-dimensional structure of the PapD chaperone. The consensus sequence for twelve members of the family was superimposed on the tertiary structure of PapD. The position of the invariant amino acid residues is shown in black, and that of the residues conserved in at least eight of the sequences, in gray.

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