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Chamber scarification test

Frosch PJ, Kligman AM (1976) The chamber scarification test for irritancy. Contact Dermatitis 2 314-324... [Pg.382]

Frosch PJ, Kligman AM (1977) The chamber scarification test for assessing irritancy of topically applied substances. Cutaneous Toxicity. Academic Press, NY, pp 127-144 Frosch PJ, Kligman AM (1979) The soap chamber test. A new method for assessing the irritancy of soaps. J Am Acad Dermatol 1 35-41... [Pg.382]

Many bioassays have been proposed for the purpose of identifying sensitive skin. A 24-h patch test with sodium lauryl sulphate (SLS) and repetitive patch tests, such as the 21-day cumulative-irritation assay, the chamber scarification test, and the soap-chamber test, have been used (Lee and Maibach 1994). [Pg.103]

An abrasion is major, visible damage to the epidermis caused by friction. Abrasions facilitate the entry of allergens and irritants into the skin. Friction and other microtraumas may contribute to irritant and allergic contact dermatitis. The chamber-scarification test of Frosch and Kligman (1976) can be used to study the combined effect of abrasions and mechanical irritants. The irritation caused by abrasive materials has been reviewed by Fleming and Bergfelt (1990). [Pg.158]

See other pages where Chamber scarification test is mentioned: [Pg.491]    [Pg.497]    [Pg.370]    [Pg.382]    [Pg.160]    [Pg.491]    [Pg.497]    [Pg.370]    [Pg.382]    [Pg.160]   
See also in sourсe #XX -- [ Pg.491 , Pg.497 ]



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