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Ceramide-l-phosphate

Gomez-Munoz A, Kong JY, Salh B, Steinbrecher UP. Ceramide-l-phosphate blocks apoptosis through inhibition of acid sphingomyelinase in macrophages. / Lipid Res. 2004 45(1) 99-105. [Pg.81]

HoeferUn LA, Wijesinghe DS, Chalfant CE. The role of ceramide-l-phosphate in biological functions. Handb Exp Pharmacol. 2013 215 153-166. [Pg.82]

Morrow MR, Helle A, Perry J, Vattulainen 1, V Uedmer SK, Holopainen JM. Ceramide-l-phosphate, in contrast to ceramide, is not segregated into lateral Upid domains in phosphatidylcholine bilayers. Biophys. 2009 96(6) 2216-2226. [Pg.82]

Kooijman EE, Sot J, Montes LR, et al. Membrane organization and ionization behavior of the minor but crucial lipid ceramide-l-phosphate. Biophys ]. 2008 94(ll) 4320-4330. [Pg.82]

Fig. 12. Some signaling targets and pathways affected by sphingolipid backbones that are metabolically interrelated. PKA, protein kinase A PDKl, 3-phosphoinositide-dependent kinase 1 SDKl, sphingosine-dependent kinase 1 PKC, protein kinase C PPl, protein phosphatase 1 PP2A, protein phosphatase 2A aSMase, acid sphingomyelinase PLA, phospholipase Aj SIP, sphingosine-l-phosphase MATIA, methionine adenosyl-transferase (liver specific) SFl, steroidogenic factor 1. The biophysical properties of ceramides and ceramide 1-phosphates may play important roles in membrane structure, including tendencies to form rafts, membrane curvature, and leakiness. Fig. 12. Some signaling targets and pathways affected by sphingolipid backbones that are metabolically interrelated. PKA, protein kinase A PDKl, 3-phosphoinositide-dependent kinase 1 SDKl, sphingosine-dependent kinase 1 PKC, protein kinase C PPl, protein phosphatase 1 PP2A, protein phosphatase 2A aSMase, acid sphingomyelinase PLA, phospholipase Aj SIP, sphingosine-l-phosphase MATIA, methionine adenosyl-transferase (liver specific) SFl, steroidogenic factor 1. The biophysical properties of ceramides and ceramide 1-phosphates may play important roles in membrane structure, including tendencies to form rafts, membrane curvature, and leakiness.
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See also in sourсe #XX -- [ Pg.71 ]



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