Ceramic-biomolecules nanocomposites

Biomolecules are the desired matrix materials for fabricating nanocomposites. Biomolecules are a suitable platform for cells to attach and proliferate, which comes from their structures and compositions that more closely resemble to extracellular matrix. Their highly hierarchical and anisotropic structures are particularly difficult to replicate on synthetic materials. Therefore, biomolecule matrix is a much easier way toward high biological performance of nanocomposite. Because of well-established material technologies that can successfully incorporate, reinforce, and precisely control the structure and properties of different phases (nanoparticles, nanombes, nanofibers, etc.), ceramic-biomolecule nanocomposites are promising to achieve both superior biological performance and desired mechanical properties. For example, to... 

HA/silica gel was studied as a tissue engineering scaffold for the delivery of BMSCs and platelet-rich growth factor and results indicated that this nanoscaffold-assisted strategy was more effective for bone regeneration in vivo compared to the treatment without nanoscaffold [93]. There are a lot of studies on composite nanoscaffolds composed of ceramics and other materials (mostly polymers or biomolecules) and Chapter 4 will deliver a comprehensive review on these nanocomposites. 

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