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Cephalotaxus esters, antitumor activity

Cephalotaxine (189) is a representative Cephalotaxus alkaloid several ester derivatives, both natural products and semisynthetic ones, were found to exhibit significant antitumor activity (85MI3). Syntheses of cephalotaxinones 44 (Section III,D) and 109 (Section IV,A,4) have been mentioned. [Pg.69]

VI. Unnatural Cephalotaxus Esters and Their Antitumor Activity. 254... [Pg.199]

The slowly growing tree Cephalotaxus harringtonia is the source of cephalotaxine (12) and its esters harringtonine (13), deoxyharringtonine, isoharringtonine, and homoharringtonine. These compounds have shown significant antitumor activity. Production of these alkaloids by means of cell and tissue cultures has been patented (see Table XXI). [Pg.74]

See other pages where Cephalotaxus esters, antitumor activity is mentioned: [Pg.44]    [Pg.292]   
See also in sourсe #XX -- [ Pg.254 , Pg.255 , Pg.256 , Pg.257 , Pg.258 , Pg.259 , Pg.260 ]



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Activated esters

Active ester

Antitumor activity

Antitumoral activity

Cephalotaxus

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